KLIFS - the structural kinase database

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Searching for structures with analogs of Fasudil.

Search results (21 entries covering 11 PDB structures)

Search in this table:

Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Similarity (MFP)
CDC42BPB (MRCKb)	DMPK	AGC	3tku	A		5-(1,4-diazepan-1-sulfonyl)isoquinoline	Human	1.00
CDC42BPB (MRCKb)	DMPK	AGC	3tku	B		5-(1,4-diazepan-1-sulfonyl)isoquinoline	Human	1.00
PAK4	STE20	STE	5vef	A	A	5-(1,4-diazepan-1-sulfonyl)isoquinoline	Human	1.00
PAK4	STE20	STE	5vef	A	B	5-(1,4-diazepan-1-sulfonyl)isoquinoline	Human	1.00
ROCK1	DMPK	AGC	2esm	A		5-(1,4-diazepan-1-sulfonyl)isoquinoline	Human	1.00
ROCK1	DMPK	AGC	2esm	B		5-(1,4-diazepan-1-sulfonyl)isoquinoline	Human	1.00
Prkaca (PKACa)	PKA	AGC	2erz	E		1-(1-hydroxy-5-isoquinolinesulfonyl)homopiperazine	Mouse	0.63
ROCK1	DMPK	AGC	2etk	A		1-(1-hydroxy-5-isoquinolinesulfonyl)homopiperazine	Human	0.63
ROCK1	DMPK	AGC	2etk	B		1-(1-hydroxy-5-isoquinolinesulfonyl)homopiperazine	Human	0.63
DAPK2	DAPK	CAMK	2cke	A		n-(2-aminoethyl)isoquinoline-5-sulfonamide	Human	0.48
DAPK2	DAPK	CAMK	2cke	B		n-(2-aminoethyl)isoquinoline-5-sulfonamide	Human	0.48
DAPK2	DAPK	CAMK	2cke	C		n-(2-aminoethyl)isoquinoline-5-sulfonamide	Human	0.48
DAPK2	DAPK	CAMK	2cke	D		n-(2-aminoethyl)isoquinoline-5-sulfonamide	Human	0.48
AKT2	Akt	AGC	2jdo	A		isoquinoline-5-sulfonic acid (2-(2-(4-chlorobenzyloxy)ethylamino)ethyl)amide	Human	0.44
HASPIN (Haspin)	Haspin	Other	3fmd	A	A	n-[2-(4-bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide	Human	0.44
HASPIN (Haspin)	Haspin	Other	3fmd	A	B	n-[2-(4-bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide	Human	0.44
PRKACA (PKACa)	PKA	AGC	3vqh	A	A	n-[2-(4-bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide	Human	0.44
PRKACA (PKACa)	PKA	AGC	3vqh	A	B	n-[2-(4-bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide	Human	0.44
ROCK1	DMPK	AGC	3d9v	A		(s)-2-methyl-1-[(4-methyl-5-isoquinoline)sulfonyl]-homopiperazine	Human	0.43
ROCK1	DMPK	AGC	3d9v	B		(s)-2-methyl-1-[(4-methyl-5-isoquinoline)sulfonyl]-homopiperazine	Human	0.43

Showing 1 to 20 of 21 entries

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