Searching for structures with analogs of Fasudil.
Search results (21 entries covering 11 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| ROCK1 | DMPK | AGC | 3d9v | A | (s)-2-methyl-1-[(4-methyl-5-isoquinoline)sulfonyl]-homopiperazine | Human | 2696 | 0.43 | |||
| CSNK2A1 (CK2a1) | CK2 | CMGC | 8pvp | A | ~{n}-[5-[(3-chloranyl-4-phenyl-phenyl)methylamino]pentyl]isoquinoline-5-sulfonamide | Human | 14977 | 0.40 | |||
| DAPK2 | DAPK | CAMK | 2cke | B | n-(2-aminoethyl)isoquinoline-5-sulfonamide | Human | 1132 | 0.48 | |||
| DAPK2 | DAPK | CAMK | 2cke | C | n-(2-aminoethyl)isoquinoline-5-sulfonamide | Human | 1135 | 0.48 | |||
| CDC42BPB (MRCKb) | DMPK | AGC | 3tku | B | 5-(1,4-diazepan-1-sulfonyl)isoquinoline | Human | 4859 | 1.00 | |||
| PRKACA (PKACa) | PKA | AGC | 3vqh | A | A | n-[2-(4-bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide | Human | 5271 | 0.44 | ||
| DAPK2 | DAPK | CAMK | 2cke | D | n-(2-aminoethyl)isoquinoline-5-sulfonamide | Human | 1141 | 0.48 | |||
| AKT2 | Akt | AGC | 2jdo | A | isoquinoline-5-sulfonic acid (2-(2-(4-chlorobenzyloxy)ethylamino)ethyl)amide | Human | 1922 | 0.44 | |||
| ROCK1 | DMPK | AGC | 2etk | A | 1-(1-hydroxy-5-isoquinolinesulfonyl)homopiperazine | Human | 2707 | 0.63 | |||
| ROCK1 | DMPK | AGC | 2esm | A | 5-(1,4-diazepan-1-sulfonyl)isoquinoline | Human | 2726 | 1.00 | |||
| ROCK1 | DMPK | AGC | 2etk | B | 1-(1-hydroxy-5-isoquinolinesulfonyl)homopiperazine | Human | 2723 | 0.63 | |||
| DAPK2 | DAPK | CAMK | 2cke | A | n-(2-aminoethyl)isoquinoline-5-sulfonamide | Human | 1143 | 0.48 | |||
| CDC42BPB (MRCKb) | DMPK | AGC | 3tku | A | 5-(1,4-diazepan-1-sulfonyl)isoquinoline | Human | 4862 | 1.00 | |||
| PRKACA (PKACa) | PKA | AGC | 3vqh | A | B | n-[2-(4-bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide | Human | 5275 | 0.44 | ||
| HASPIN (Haspin) | Haspin | Other | 3fmd | A | B | n-[2-(4-bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide | Human | 3810 | 0.44 | ||
| HASPIN (Haspin) | Haspin | Other | 3fmd | A | A | n-[2-(4-bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide | Human | 3798 | 0.44 | ||
| PAK4 | STE20 | STE | 5vef | A | B | 5-(1,4-diazepan-1-sulfonyl)isoquinoline | Human | 8571 | 1.00 | ||
| PAK4 | STE20 | STE | 5vef | A | A | 5-(1,4-diazepan-1-sulfonyl)isoquinoline | Human | 8569 | 1.00 | ||
| ROCK1 | DMPK | AGC | 3d9v | B | (s)-2-methyl-1-[(4-methyl-5-isoquinoline)sulfonyl]-homopiperazine | Human | 2701 | 0.43 | |||
| ROCK1 | DMPK | AGC | 2esm | B | 5-(1,4-diazepan-1-sulfonyl)isoquinoline | Human | 2714 | 1.00 | |||
| Prkaca (PKACa) | PKA | AGC | 2erz | E | 1-(1-hydroxy-5-isoquinolinesulfonyl)homopiperazine | Mouse | 5895 | 0.63 |
Fasudil
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