Searching for structures with analogs of Enzastaurin.
Search results (8 entries covering 5 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| PIM1 | PIM | CAMK | 2j2i | B | A | (9r)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydro-9h,18h-5,21:12,17-dimethenodibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20-dione | Human | 2318 | 0.41 | ||
| PDPK1 (PDK1) | PDK1 | AGC | 1uu3 | A | A | (9r)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydro-9h,18h-5,21:12,17-dimethenodibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20-dione | Human | 3180 | 0.41 | ||
| PRKCB (PKCb) | PKC | AGC | 9s9t | A | (9r)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydro-9h,18h-5,21:12,17-dimethenodibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20-dione | Human | 16135 | 0.41 | |||
| PIM1 | PIM | CAMK | 2j2i | B | B | (9r)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydro-9h,18h-5,21:12,17-dimethenodibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20-dione | Human | 2434 | 0.41 | ||
| DMPK (DMPK1) | DMPK | AGC | 2vd5 | A | 3-[1-(3-aminopropyl)-1h-indol-3-yl]-4-(1-methyl-1h-indol-3-yl)-1h-pyrrole-2,5-dione | Human | 1901 | 0.44 | |||
| PDPK1 (PDK1) | PDK1 | AGC | 1uvr | A | 3-[1-(3-aminopropyl)-1h-indol-3-yl]-4-(1-methyl-1h-indol-3-yl)-1h-pyrrole-2,5-dione | Human | 3193 | 0.44 | |||
| DMPK (DMPK1) | DMPK | AGC | 2vd5 | B | 3-[1-(3-aminopropyl)-1h-indol-3-yl]-4-(1-methyl-1h-indol-3-yl)-1h-pyrrole-2,5-dione | Human | 1902 | 0.44 | |||
| PDPK1 (PDK1) | PDK1 | AGC | 1uu3 | A | B | (9r)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydro-9h,18h-5,21:12,17-dimethenodibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20-dione | Human | 3248 | 0.41 |
Enzastaurin
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