Searching for structures with analogs of Ansornitinib.
Search results (16 entries covering 6 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| KDR | VEGFR | TK | 3c7q | A | methyl (3z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}phenyl)amino](phenyl)methylidene}-2-oxo-2,3-dihydro-1h-indole-6-carboxylate | Human | 5334 | 0.78 | |||
| RET | Ret | TK | 6nec | A | A | methyl (3z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}phenyl)amino](phenyl)methylidene}-2-oxo-2,3-dihydro-1h-indole-6-carboxylate | Human | 11151 | 0.78 | ||
| RET | Ret | TK | 6nec | C | B | methyl (3z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}phenyl)amino](phenyl)methylidene}-2-oxo-2,3-dihydro-1h-indole-6-carboxylate | Human | 11153 | 0.78 | ||
| RET | Ret | TK | 6nec | A | B | methyl (3z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}phenyl)amino](phenyl)methylidene}-2-oxo-2,3-dihydro-1h-indole-6-carboxylate | Human | 11150 | 0.78 | ||
| AAK1 | NAK | Other | 5te0 | A | methyl (3z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}phenyl)amino](phenyl)methylidene}-2-oxo-2,3-dihydro-1h-indole-6-carboxylate | Human | 7156 | 0.78 | |||
| TGFBR1 (TGFbR1) | STKR | TKL | 2x7o | E | (3z)-n-ethyl-n-methyl-2-oxo-3-(phenyl{[4-(piperidin-1-ylmethyl)phenyl]amino}methylidene)-2,3-dihydro-1h-indole-6-carboxamide | Human | 2097 | 0.45 | |||
| TGFBR1 (TGFbR1) | STKR | TKL | 2x7o | C | (3z)-n-ethyl-n-methyl-2-oxo-3-(phenyl{[4-(piperidin-1-ylmethyl)phenyl]amino}methylidene)-2,3-dihydro-1h-indole-6-carboxamide | Human | 2104 | 0.45 | |||
| TGFBR1 (TGFbR1) | STKR | TKL | 2x7o | A | (3z)-n-ethyl-n-methyl-2-oxo-3-(phenyl{[4-(piperidin-1-ylmethyl)phenyl]amino}methylidene)-2,3-dihydro-1h-indole-6-carboxamide | Human | 2127 | 0.45 | |||
| ULK2 | ULK | Other | 6qat | B | n-{(3z)-2-oxo-3-[phenyl({4-[(piperidin-1-yl)methyl]phenyl}amino)methylidene]-2,3-dihydro-1h-indol-5-yl}ethanesulfonamide | Human | 11226 | 0.41 | |||
| MELK | CAMKL | CAMK | 5maf | A | methyl (3z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}phenyl)amino](phenyl)methylidene}-2-oxo-2,3-dihydro-1h-indole-6-carboxylate | Human | 8732 | 0.78 | |||
| RET | Ret | TK | 6nec | C | A | methyl (3z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}phenyl)amino](phenyl)methylidene}-2-oxo-2,3-dihydro-1h-indole-6-carboxylate | Human | 11147 | 0.78 | ||
| ULK2 | ULK | Other | 6qat | D | n-{(3z)-2-oxo-3-[phenyl({4-[(piperidin-1-yl)methyl]phenyl}amino)methylidene]-2,3-dihydro-1h-indol-5-yl}ethanesulfonamide | Human | 11230 | 0.41 | |||
| ULK2 | ULK | Other | 6qat | C | n-{(3z)-2-oxo-3-[phenyl({4-[(piperidin-1-yl)methyl]phenyl}amino)methylidene]-2,3-dihydro-1h-indol-5-yl}ethanesulfonamide | Human | 11232 | 0.41 | |||
| ULK2 | ULK | Other | 6qat | A | n-{(3z)-2-oxo-3-[phenyl({4-[(piperidin-1-yl)methyl]phenyl}amino)methylidene]-2,3-dihydro-1h-indol-5-yl}ethanesulfonamide | Human | 11227 | 0.41 | |||
| TGFBR1 (TGFbR1) | STKR | TKL | 2x7o | D | (3z)-n-ethyl-n-methyl-2-oxo-3-(phenyl{[4-(piperidin-1-ylmethyl)phenyl]amino}methylidene)-2,3-dihydro-1h-indole-6-carboxamide | Human | 2107 | 0.45 | |||
| TGFBR1 (TGFbR1) | STKR | TKL | 2x7o | B | (3z)-n-ethyl-n-methyl-2-oxo-3-(phenyl{[4-(piperidin-1-ylmethyl)phenyl]amino}methylidene)-2,3-dihydro-1h-indole-6-carboxamide | Human | 2128 | 0.45 |
Ansornitinib
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