Searching for structures with analogs of -.
Search results (8 entries covering 7 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| AURKA (AurA) | Aur | Other | 5aad | A | 7-(1-benzyl-1h-pyrazol-4-yl)-6-chloro-2-(1,3-dimethyl-1h-pyrazol-4-yl)-3h-imidazo[4,5-b]pyridine | Human | 6011 | 0.55 | |||
| AURKA (AurA) | Aur | Other | 2x6d | A | A | 6-bromo-7-[4-(4-chlorobenzyl)piperazin-1-yl]-2-[4-(morpholin-4-ylmethyl)phenyl]-3h-imidazo[4,5-b]pyridine | Human | 1978 | 0.56 | ||
| AURKA (AurA) | Aur | Other | 2x6d | A | B | 6-bromo-7-[4-(4-chlorobenzyl)piperazin-1-yl]-2-[4-(morpholin-4-ylmethyl)phenyl]-3h-imidazo[4,5-b]pyridine | Human | 1975 | 0.56 | ||
| AURKA (AurA) | Aur | Other | 5aae | A | 3-((4-(6-chloro-2-(1,3-dimethyl-1h-pyrazol-4-yl)-3h-imidazo[4,5-b]pyridin-7-yl)-1h-pyrazol-1-yl)methyl)-5-methylisoxazole | Human | 6012 | 0.43 | |||
| AURKA (AurA) | Aur | Other | 2x6e | A | 6-bromo-7-{4-[(5-methylisoxazol-3-yl)methyl]piperazin-1-yl}-2-[4-(4-methylpiperazin-1-yl)phenyl]-1h-imidazo[4,5-b]pyridine | Human | 2079 | 0.44 | |||
| AURKA (AurA) | Aur | Other | 4byi | A | (s)-n-((1-(6-chloro-2-(1,3-dimethyl-1h-pyrazol-4-yl)-3h-imidazo[4,5-b]pyridin-7-yl)pyrrolidin-3-yl)methyl)acetamide | Human | 1992 | 0.55 | |||
| AURKA (AurA) | Aur | Other | 4byj | A | (s)-n-(1-(6-chloro-2-(1,3-dimethyl-1h-pyrazol-4-yl)-3h-imidazo[4,5-b]pyridin-7-yl)pyrrolidin-3-yl)acetamide | Human | 1969 | 0.56 | |||
| AURKA (AurA) | Aur | Other | 5aag | A | [3-[[4-[6-chloranyl-2-(1,3-dimethylpyrazol-4-yl)-3h-imidazo[4,5-b]pyridin-7-yl]pyrazol-1-yl]methyl]phenyl]-(4-methylpiperazin-1-yl)methanone | Human | 6010 | 0.48 |
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