Searching for structures with analogs of -.
Search results (6 entries covering 3 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| TYK2-b | JakB | TK | 8s99 | A | A | (8s)-n-[(1r,2s)-2-fluorocyclopropyl]-5-{[(1m,2'm)-3'-fluoro-2-oxo-2h-[1,2'-bipyridin]-3-yl]amino}-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | 14847 | 0.62 | ||
| TYK2-b | JakB | TK | 8s98 | A | A | (8s)-n-cyclopropyl-5-[(2-methoxypyridin-3-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | 14849 | 0.62 | ||
| TYK2-b | JakB | TK | 8s98 | A | B | (8s)-n-cyclopropyl-5-[(2-methoxypyridin-3-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | 14846 | 0.62 | ||
| TYK2-b | JakB | TK | 8s9a | A | A | (8s)-n-[(1r,2r)-2-methoxycyclobutyl]-7-(methylamino)-5-{[(1p,2'p)-2-oxo-2h-[1,2'-bipyridin]-3-yl]amino}pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | 14848 | 1.00 | ||
| TYK2-b | JakB | TK | 8s99 | A | B | (8s)-n-[(1r,2s)-2-fluorocyclopropyl]-5-{[(1m,2'm)-3'-fluoro-2-oxo-2h-[1,2'-bipyridin]-3-yl]amino}-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | 14850 | 0.62 | ||
| TYK2-b | JakB | TK | 8s9a | A | B | (8s)-n-[(1r,2r)-2-methoxycyclobutyl]-7-(methylamino)-5-{[(1p,2'p)-2-oxo-2h-[1,2'-bipyridin]-3-yl]amino}pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | 14851 | 1.00 |
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