KLIFS - the structural kinase database

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Searching for structures with analogs of -.

Search results (91 entries covering 51 PDB structures)

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Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Similarity (MFP)
BRAF	RAF	TKL	4jvg	A		1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea	Human	0.62
BRAF	RAF	TKL	4jvg	B		1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea	Human	0.62
BRAF	RAF	TKL	4jvg	C		1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea	Human	0.62
BRAF	RAF	TKL	4jvg	D		1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea	Human	0.62
EPHA3 (EphA3)	Eph	TK	4twn	A	A	1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea	Human	0.62
EPHA3 (EphA3)	Eph	TK	4twn	A	B	1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea	Human	0.62
MAPK11 (p38b)	MAPK	CMGC	8ygw	A		1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea	Human	0.62
MAPK14 (p38a)	MAPK	CMGC	1kv2	A		1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea	Human	0.62
MAPK14 (p38a)	MAPK	CMGC	5n66	A		1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea	Human	0.62
MAPK9 (JNK2)	MAPK	CMGC	3npc	A		1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea	Human	0.62
MAPK9 (JNK2)	MAPK	CMGC	3npc	B		1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea	Human	0.62
PTK2B (PYK2)	FAK	TK	3fzs	A		1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea	Human	0.62
STK10 (LOK)	STE20	STE	6gtt	A	A	1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea	Human	0.62
STK10 (LOK)	STE20	STE	6gtt	A	B	1-(5-tert-butyl-2-p-tolyl-2h-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea	Human	0.62
MAPK14 (p38a)	MAPK	CMGC	3nnv	A	A	1-{3-tert-butyl-1-[4-(hydroxymethyl)phenyl]-1h-pyrazol-5-yl}-3-naphthalen-1-ylurea	Human	0.53
MAPK14 (p38a)	MAPK	CMGC	3nnv	A	B	1-{3-tert-butyl-1-[4-(hydroxymethyl)phenyl]-1h-pyrazol-5-yl}-3-naphthalen-1-ylurea	Human	0.53
MAPK14 (p38a)	MAPK	CMGC	3lfb	A	A	1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-(1,3-thiazol-2-yl)urea	Human	0.49
MAPK14 (p38a)	MAPK	CMGC	3lfb	A	B	1-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]-3-(1,3-thiazol-2-yl)urea	Human	0.49
MAPK14 (p38a)	MAPK	CMGC	3hv4	A		1-{3-[(6-aminoquinolin-4-yl)amino]phenyl}-3-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]urea	Human	0.48
MAPK14 (p38a)	MAPK	CMGC	3hv4	B		1-{3-[(6-aminoquinolin-4-yl)amino]phenyl}-3-[3-tert-butyl-1-(4-methylphenyl)-1h-pyrazol-5-yl]urea	Human	0.48

Showing 1 to 20 of 91 entries

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