Searching for structures with analogs of Dabrafenib.
Search results (17 entries covering 7 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| BRAF | RAF | TKL | 5csw | A | dabrafenib | Human | 6433 | 1.00 | |||
| BRAF | RAF | TKL | 6v2u | A | dabrafenib | Human | 13034 | 1.00 | |||
| BRAF | RAF | TKL | 7p3v | A | ~{n}-[3-[5-(2-azanylpyrimidin-4-yl)-2-[(3~{s})-morpholin-3-yl]-1,3-thiazol-4-yl]-2-fluoranyl-phenyl]-2,5-bis(fluoranyl)benzenesulfonamide | Human | 13961 | 0.53 | |||
| BRAF | RAF | TKL | 5hie | D | A | dabrafenib | Human | 6510 | 1.00 | ||
| BRAF | RAF | TKL | 5hie | A | A | dabrafenib | Human | 6516 | 1.00 | ||
| BRAF | RAF | TKL | 4xv3 | A | n'-{3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl}-n-ethyl-n-methylsulfuric diamide | Human | 6217 | 0.70 | |||
| BRAF | RAF | TKL | 5hie | C | B | dabrafenib | Human | 6507 | 1.00 | ||
| BRAF | RAF | TKL | 5csw | B | dabrafenib | Human | 6431 | 1.00 | |||
| BRAF | RAF | TKL | 5hie | C | A | dabrafenib | Human | 6513 | 1.00 | ||
| BRAF | RAF | TKL | 5hie | D | B | dabrafenib | Human | 6514 | 1.00 | ||
| BRAF | RAF | TKL | 6v2u | B | dabrafenib | Human | 13031 | 1.00 | |||
| BRAF | RAF | TKL | 5hie | B | A | dabrafenib | Human | 6509 | 1.00 | ||
| EIF2AK2 (PKR) | PEK | Other | 9yuf | A | dabrafenib | Human | 15962 | 1.00 | |||
| BRAF | RAF | TKL | 5hie | B | B | dabrafenib | Human | 6505 | 1.00 | ||
| BRAF | RAF | TKL | 4xv2 | A | dabrafenib | Human | 6213 | 1.00 | |||
| BRAF | RAF | TKL | 4xv2 | B | dabrafenib | Human | 6219 | 1.00 | |||
| BRAF | RAF | TKL | 5hie | A | B | dabrafenib | Human | 6508 | 1.00 |
Dabrafenib
Match:![]()