KLIFS - the structural kinase database

Searching for structures with analogs of -.

Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details	Similarity (MFP)
Pik3cd (p110d)	PIK	Atypical	5ae8	A		6-(1h-indol-4-yl)-4-(5-{[4-(1-methylethyl)-1-piperazinyl]methyl}-1,3-oxazol-2-yl)-1h-indazole	Mouse	9390	0.42
Pik3cd (p110d)	PIK	Atypical	6tnr	A	A	~{n}-[2-methoxy-5-[7-[2-[4-(2-oxidanylpropan-2-yl)piperidin-1-yl]ethoxy]-1,3-dihydro-2-benzofuran-5-yl]pyridin-3-yl]methanesulfonamide	Mouse	11911	0.43
Pik3cd (p110d)	PIK	Atypical	6tnr	A	B	~{n}-[2-methoxy-5-[7-[2-[4-(2-oxidanylpropan-2-yl)piperidin-1-yl]ethoxy]-1,3-dihydro-2-benzofuran-5-yl]pyridin-3-yl]methanesulfonamide	Mouse	11910	0.43
PIK3CD (p110d)	PIK	Atypical	7lq1	A		n-(5-(6-(2-((2s,6r)-2,6-dimethylmorpholino)pyridin-4-yl)-1-oxoisoindolin-4-yl)-2-methoxypyridin-3-yl)methanesulfonamide	Human	14106	0.48
Pik3cd (p110d)	PIK	Atypical	6ez6	A		methyl 2-methoxy-5-[4-[5-[(4-propan-2-ylpiperazin-1-yl)methyl]-1,3-oxazol-2-yl]-2~{h}-indazol-6-yl]pyridine-3-carboxylate	Mouse	9460	0.45
Pik3cd (p110d)	PIK	Atypical	5ae9	A		n-[5-[4-(5-{[(2r,6s)-2,6-dimethyl-4-morpholinyl]methyl}-1,3-oxazol-2-yl)-1h-indazol-6-yl]-2-(methyloxy)-3-pyridinyl]methanesulfonamide	Mouse	9372	1.00
Pik3cd (p110d)	PIK	Atypical	5l72	A		n-[6-(5-methanesulfonamido-6-methoxypyridin-3-yl)-1,3-dihydro-2-benzofuran-4-yl]-2-(morpholin-4-yl)acetamide	Mouse	9386	0.40
Pik3cd (p110d)	PIK	Atypical	6eyz	A		2-methoxy-5-[4-[5-[(4-propan-2-ylpiperazin-1-yl)methyl]-1,3-oxazol-2-yl]-2~{h}-indazol-6-yl]pyridine-3-carboxylic acid	Mouse	9426	0.44