KLIFS - the structural kinase database

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Searching for structures with analogs of -.

Search results (22 entries covering 13 PDB structures)

Search in this table:

Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Similarity (MFP)
CDK1 (CDC2)	CDK	CMGC	6gu3	A		4-(2-methyl-3-propan-2-yl-imidazol-4-yl)-~{n}-(4-methylsulfonylphenyl)pyrimidin-2-amine	Human	1.00
CDK1 (CDC2)	CDK	CMGC	6gu7	A		4-(2-methyl-3-propan-2-yl-imidazol-4-yl)-~{n}-(4-methylsulfonylphenyl)pyrimidin-2-amine	Human	1.00
CDK2	CDK	CMGC	6gue	A		4-(2-methyl-3-propan-2-yl-imidazol-4-yl)-~{n}-(4-methylsulfonylphenyl)pyrimidin-2-amine	Human	1.00
CDK2	CDK	CMGC	6gue	C		4-(2-methyl-3-propan-2-yl-imidazol-4-yl)-~{n}-(4-methylsulfonylphenyl)pyrimidin-2-amine	Human	1.00
CDK2	CDK	CMGC	6guh	A	A	4-(2-methyl-3-propan-2-yl-imidazol-4-yl)-~{n}-(4-methylsulfonylphenyl)pyrimidin-2-amine	Human	1.00
CDK2	CDK	CMGC	6guh	A	B	4-(2-methyl-3-propan-2-yl-imidazol-4-yl)-~{n}-(4-methylsulfonylphenyl)pyrimidin-2-amine	Human	1.00
CDK2	CDK	CMGC	2w05	A	A	n-(2-methoxyethyl)-4-({4-[2-methyl-1-(1-methylethyl)-1h-imidazol-5-yl]pyrimidin-2-yl}amino)benzenesulfonamide	Human	0.68
CDK2	CDK	CMGC	2w05	A	B	n-(2-methoxyethyl)-4-({4-[2-methyl-1-(1-methylethyl)-1h-imidazol-5-yl]pyrimidin-2-yl}amino)benzenesulfonamide	Human	0.68
CDK2	CDK	CMGC	2vv9	A	A	2-{4-[4-({4-[2-methyl-1-(1-methylethyl)-1h-imidazol-5-yl]pyrimidin-2-yl}amino)phenyl]piperazin-1-yl}-2-oxoethanol	Human	0.62
CDK2	CDK	CMGC	2vv9	A	B	2-{4-[4-({4-[2-methyl-1-(1-methylethyl)-1h-imidazol-5-yl]pyrimidin-2-yl}amino)phenyl]piperazin-1-yl}-2-oxoethanol	Human	0.62
CDK2	CDK	CMGC	2w06	A		4-{[4-(1-cyclopropyl-2-methyl-1h-imidazol-5-yl)pyrimidin-2-yl]amino}-n-methylbenzenesulfonamide	Human	0.57
CDK2	CDK	CMGC	1oit	A		4-[(4-imidazo[1,2-a]pyridin-3-ylpyrimidin-2-yl)amino]benzenesulfonamide	Human	0.48
CDK2	CDK	CMGC	1urw	A	A	2-[4-(n-(3-dimethylaminopropyl)sulphamoyl)anilino]-	Human	0.43
CDK2	CDK	CMGC	1urw	A	B	2-[4-(n-(3-dimethylaminopropyl)sulphamoyl)anilino]-	Human	0.43
CDK2	CDK	CMGC	2w17	A	A	n-(4-{[(3s)-3-(dimethylamino)pyrrolidin-1-yl]carbonyl}phenyl)-5-fluoro-4-[2-methyl-1-(1-methylethyl)-1h-imidazol-5-yl]pyrimidin-2-amine	Human	0.41
CDK2	CDK	CMGC	2w17	A	B	n-(4-{[(3s)-3-(dimethylamino)pyrrolidin-1-yl]carbonyl}phenyl)-5-fluoro-4-[2-methyl-1-(1-methylethyl)-1h-imidazol-5-yl]pyrimidin-2-amine	Human	0.41
CDK2	CDK	CMGC	2xmy	A	A	4-[4-(3,4-dimethyl-2-oxo-2,3-dihydro-thiazol-5-yl)-pyrimidin-2-ylamino]-n-(2-methoxy-ethyl)-benzenesulfonamide	Human	0.41
CDK2	CDK	CMGC	2xmy	A	B	4-[4-(3,4-dimethyl-2-oxo-2,3-dihydro-thiazol-5-yl)-pyrimidin-2-ylamino]-n-(2-methoxy-ethyl)-benzenesulfonamide	Human	0.41
CDK2	CDK	CMGC	5iey	A	A	4-[(4-{[(2r,3r)-3-hydroxybutan-2-yl]amino}pyrimidin-2-yl)amino]benzene-1-sulfonamide	Human	0.41
CDK2	CDK	CMGC	5iey	A	B	4-[(4-{[(2r,3r)-3-hydroxybutan-2-yl]amino}pyrimidin-2-yl)amino]benzene-1-sulfonamide	Human	0.41

Showing 1 to 20 of 22 entries

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