Searching for structures with analogs of -.
Search results (6 entries covering 6 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| PIK3CG (p110g) | PIK | Atypical | 3pre | A | 2-amino-8-(trans-4-methoxycyclohexyl)-4-methyl-6-(1h-pyrazol-3-yl)pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 9198 | 0.54 | |||
| PIK3CG (p110g) | PIK | Atypical | 3ml8 | A | 8-cyclopentyl-6-[3-(hydroxymethyl)phenyl]-4-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 9192 | 0.42 | |||
| PIK3CG (p110g) | PIK | Atypical | 3ml9 | A | 2-amino-8-[trans-4-(2-hydroxyethoxy)cyclohexyl]-6-(6-methoxypyridin-3-yl)-4-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 9187 | 1.00 | |||
| PIK3CG (p110g) | PIK | Atypical | 4fa6 | A | 2-amino-8-cyclopentyl-4-methyl-6-(1h-pyrazol-4-yl)pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 9191 | 0.54 | |||
| PIK3CG (p110g) | PIK | Atypical | 4fad | A | 2-amino-6-(5-fluoro-6-methoxypyridin-3-yl)-4-methyl-8-(pyrrolidin-1-yl)pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 9202 | 0.45 | |||
| PIK3CA (p110a) | PIK | Atypical | 4tv3 | A | 2-amino-8-[trans-4-(2-hydroxyethoxy)cyclohexyl]-6-(6-methoxypyridin-3-yl)-4-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 9278 | 1.00 |
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