Searching for structures with analogs of -.
Search results (16 entries covering 10 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MAP2K1 | STE7 | STE | 2p55 | A | 2-[(4-ethynyl-2-fluorophenyl)amino]-3,4-difluoro-n-(2-hydroxyethoxy)benzamide | Human | 3327 | 0.51 | |||
| MAP2K1 | STE7 | STE | 7m0t | B | 5-[(4-bromo-2-chlorophenyl)amino]-4-fluoro-n-(2-hydroxyethoxy)-1-methyl-1h-benzimidazole-6-carboxamide | Human | 13512 | 0.40 | |||
| MAP2K1 | STE7 | STE | 6q0j | C | A | 5-[(2-fluoro-4-iodophenyl)amino]-n-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide | Human | 11721 | 0.40 | ||
| MAP2K1 | STE7 | STE | 3eqc | A | A | 2-[(2-chloro-4-iodophenyl)amino]-n-{[(2r)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamide | Human | 3280 | 0.69 | ||
| MAP2K1 | STE7 | STE | 6q0t | C | B | 5-[(2-fluoro-4-iodophenyl)amino]-n-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide | Human | 11717 | 0.40 | ||
| MAP2K1 | STE7 | STE | 6q0j | C | B | 5-[(2-fluoro-4-iodophenyl)amino]-n-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide | Human | 11713 | 0.40 | ||
| MAP2K1 | STE7 | STE | 6q0t | C | A | 5-[(2-fluoro-4-iodophenyl)amino]-n-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide | Human | 11715 | 0.40 | ||
| MAP2K1 | STE7 | STE | 13dv | C | 5-[(2-fluoro-4-iodophenyl)amino]-n-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide | Human | 16183 | 0.40 | |||
| MAP2K1 | STE7 | STE | 4anb | A | [3-(aminomethyl)-3-oxidanyl-azetidin-1-yl]-[3,4-bis(fluoranyl)-2-[(2-fluoranyl-4-iodanyl-phenyl)amino]phenyl]methanone | Human | 3302 | 0.45 | |||
| MAP2K1 | STE7 | STE | 4an2 | A | A | [3,4-bis(fluoranyl)-2-[(2-fluoranyl-4-iodanyl-phenyl)amino]phenyl]-[3-oxidanyl-3-[(2s)-piperidin-2-yl]azetidin-1-yl]methanone | Human | 3309 | 0.44 | ||
| MAP2K1 | STE7 | STE | 6q0j | D | B | 5-[(2-fluoro-4-iodophenyl)amino]-n-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide | Human | 11718 | 0.40 | ||
| MAP2K1 | STE7 | STE | 3v04 | A | 4-[(2-fluoro-4-iodophenyl)amino]-n-(2-hydroxyethoxy)-1h-indazole-5-carboxamide | Human | 3325 | 0.43 | |||
| MAP2K1 | STE7 | STE | 3eqc | A | B | 2-[(2-chloro-4-iodophenyl)amino]-n-{[(2r)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamide | Human | 3300 | 0.69 | ||
| MAP2K1 | STE7 | STE | 4u7z | A | 5-[(4-bromo-2-chlorophenyl)amino]-4-fluoro-n-(2-hydroxyethoxy)-1-methyl-1h-benzimidazole-6-carboxamide | Human | 3297 | 0.40 | |||
| MAP2K1 | STE7 | STE | 6q0j | D | A | 5-[(2-fluoro-4-iodophenyl)amino]-n-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide | Human | 11714 | 0.40 | ||
| MAP2K1 | STE7 | STE | 4an2 | A | B | [3,4-bis(fluoranyl)-2-[(2-fluoranyl-4-iodanyl-phenyl)amino]phenyl]-[3-oxidanyl-3-[(2s)-piperidin-2-yl]azetidin-1-yl]methanone | Human | 3326 | 0.44 |