Searching for structures with analogs of Zimlovisertib.
Search results (8 entries covering 3 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| IRAK4 | IRAK | TKL | 5uit | A | 1-{[(2s)-5-oxopyrrolidin-2-yl]methoxy}-7-[(propan-2-yl)oxy]isoquinoline-6-carboxamide | Human | 7606 | 0.52 | |||
| IRAK4 | IRAK | TKL | 5uit | B | 1-{[(2s)-5-oxopyrrolidin-2-yl]methoxy}-7-[(propan-2-yl)oxy]isoquinoline-6-carboxamide | Human | 7597 | 0.52 | |||
| IRAK4 | IRAK | TKL | 8wtf | A | A | 1-{[(2s,3s,4s)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide | Human | 14960 | 1.00 | ||
| IRAK4 | IRAK | TKL | 5uiu | B | B | 1-{[(2s,3s,4s)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide | Human | 7609 | 1.00 | ||
| IRAK4 | IRAK | TKL | 5uiu | B | A | 1-{[(2s,3s,4s)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide | Human | 7607 | 1.00 | ||
| IRAK4 | IRAK | TKL | 5uiu | A | B | 1-{[(2s,3s,4s)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide | Human | 7615 | 1.00 | ||
| IRAK4 | IRAK | TKL | 5uiu | A | A | 1-{[(2s,3s,4s)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide | Human | 7603 | 1.00 | ||
| IRAK4 | IRAK | TKL | 8wtf | A | B | 1-{[(2s,3s,4s)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide | Human | 14963 | 1.00 |
Zimlovisertib
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