KLIFS - the structural kinase database

Searching for structures with analogs of -.

Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details	Similarity (MFP)
FGFR2	FGFR	TK	7kie	B	A	n-{4-[(e)-2-{4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1h-pyrazol-3-yl)amino]pyrimidin-2-yl}ethenyl]phenyl}prop-2-enamide	Human	13282	0.70
AURKA (AurA)	Aur	Other	3w10	A		1-(3-methoxyphenyl)-n-(5-methyl-1h-pyrazol-3-yl)isoquinolin-3-amine	Human	2068	0.42
FGFR2	FGFR	TK	7kie	B	B	n-{4-[(e)-2-{4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1h-pyrazol-3-yl)amino]pyrimidin-2-yl}ethenyl]phenyl}prop-2-enamide	Human	13284	0.70
FGFR2	FGFR	TK	7kie	A	B	n-{4-[(e)-2-{4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1h-pyrazol-3-yl)amino]pyrimidin-2-yl}ethenyl]phenyl}prop-2-enamide	Human	13286	0.70
FGFR2	FGFR	TK	7kie	A	A	n-{4-[(e)-2-{4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1h-pyrazol-3-yl)amino]pyrimidin-2-yl}ethenyl]phenyl}prop-2-enamide	Human	13287	0.70
AURKA (AurA)	Aur	Other	5zan	A		7-(4-methylpiperazin-1-yl)-n-(5-methyl-1h-pyrazol-3-yl)-2-[(e)-2-phenylethenyl]quinazolin-4-amine	Human	10898	0.66
BTK	Tec	TK	3pix	A		7-(4-methylpiperazin-1-yl)-4-[(5-methyl-1h-pyrazol-3-yl)amino]-2-(propan-2-yl)phthalazin-1(2h)-one	Human	2927	0.43