Searching for structures with analogs of -.
Search results (6 entries covering 4 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| EGFR | EGFR | TK | 5hg9 | A | B | 1-[(3r,4r)-3-[({2-[(1-methyl-1h-pyrazol-4-yl)amino]-7h-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-(trifluoromethyl)pyrrolidin-1-yl]propan-1-one | Human | 6377 | 0.48 | ||
| EGFR | EGFR | TK | 5hg7 | A | 1-{(3r,4r)-3-[({5-chloro-2-[(1-methyl-1h-pyrazol-4-yl)amino]-7h-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-methoxypyrrolidin-1-yl}propan-1-one | Human | 6367 | 0.81 | |||
| EGFR | EGFR | TK | 5hg9 | A | A | 1-[(3r,4r)-3-[({2-[(1-methyl-1h-pyrazol-4-yl)amino]-7h-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-(trifluoromethyl)pyrrolidin-1-yl]propan-1-one | Human | 6379 | 0.48 | ||
| TTK | TTK | Other | 7cil | A | B | 4-(cyclohexylamino)-2-[(1-methylpyrazol-4-yl)amino]-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | Human | 13555 | 0.41 | ||
| TTK | TTK | Other | 7cil | A | A | 4-(cyclohexylamino)-2-[(1-methylpyrazol-4-yl)amino]-7h-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | Human | 13549 | 0.41 | ||
| MAP3K7 (TAK1) | MLK | TKL | 5jk3 | A | ~{n}-[2-[5-chloranyl-2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide | Human | 7430 | 0.44 |
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