Searching for structures with analogs of -.
Search results (8 entries covering 6 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| PIK3CG (p110g) | PIK | Atypical | 3apc | A | 5-(7-methanesulfonyl-2-morpholin-4-yl-6,7-dihydro-5h-pyrrolo[2,3-d]pyrimidin-4-yl)-pyrimidin-2-ylamine | Human | 9231 | 0.50 | |||
| PIK3CG (p110g) | PIK | Atypical | 3apd | A | 5-(2-morpholin-4-yl-7-pyridin-3-yl-6,7-dihydro-5h-pyrrolo[2,3-d]pyrimidin-4-yl)-pyrimidin-2-ylamine | Human | 9205 | 0.44 | |||
| PIK3CA (p110a) | PIK | Atypical | 7k6o | A | B | (3s)-3-[4-(2-aminopyrimidin-5-yl)-2-(morpholin-4-yl)-5,6-dihydro-7h-pyrrolo[2,3-d]pyrimidin-7-yl]-n-methylpyrrolidine-1-sulfonamide | Human | 13206 | 0.41 | ||
| PIK3CG (p110g) | PIK | Atypical | 3tjp | A | n~6~-(3,4-dimethoxyphenyl)-2-(morpholin-4-yl)-4,5'-bipyrimidine-2',6-diamine | Human | 9234 | 0.40 | |||
| PIK3CA (p110a) | PIK | Atypical | 7k6n | A | B | tert-butyl (3s)-3-[4-(2-aminopyrimidin-5-yl)-2-(morpholin-4-yl)-5,6-dihydro-7h-pyrrolo[2,3-d]pyrimidin-7-yl]-3-methylpyrrolidine-1-carboxylate | Human | 13224 | 0.42 | ||
| PIK3CA (p110a) | PIK | Atypical | 7k71 | A | 2-(morpholin-4-yl)[4,5'-bipyrimidin]-2'-amine | Human | 13219 | 0.46 | |||
| PIK3CA (p110a) | PIK | Atypical | 7k6n | A | A | tert-butyl (3s)-3-[4-(2-aminopyrimidin-5-yl)-2-(morpholin-4-yl)-5,6-dihydro-7h-pyrrolo[2,3-d]pyrimidin-7-yl]-3-methylpyrrolidine-1-carboxylate | Human | 13226 | 0.42 | ||
| PIK3CA (p110a) | PIK | Atypical | 7k6o | A | A | (3s)-3-[4-(2-aminopyrimidin-5-yl)-2-(morpholin-4-yl)-5,6-dihydro-7h-pyrrolo[2,3-d]pyrimidin-7-yl]-n-methylpyrrolidine-1-sulfonamide | Human | 13207 | 0.41 |
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