KLIFS - the structural kinase database

Searching for structures with analogs of -.

Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details	Similarity (MFP)
MAP2K1	STE7	STE	2p55	A		2-[(4-ethynyl-2-fluorophenyl)amino]-3,4-difluoro-n-(2-hydroxyethoxy)benzamide	Human	3327	0.47
MAP2K1	STE7	STE	6q0j	C	A	5-[(2-fluoro-4-iodophenyl)amino]-n-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide	Human	11721	0.49
MAP2K1	STE7	STE	6q0t	C	B	5-[(2-fluoro-4-iodophenyl)amino]-n-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide	Human	11717	0.49
MAP2K1	STE7	STE	6q0j	C	B	5-[(2-fluoro-4-iodophenyl)amino]-n-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide	Human	11713	0.49
MAP2K1	STE7	STE	6q0t	C	A	5-[(2-fluoro-4-iodophenyl)amino]-n-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide	Human	11715	0.49
MAP2K1	STE7	STE	13dv	C		5-[(2-fluoro-4-iodophenyl)amino]-n-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide	Human	16183	0.49
MAP2K1	STE7	STE	4anb	A		[3-(aminomethyl)-3-oxidanyl-azetidin-1-yl]-[3,4-bis(fluoranyl)-2-[(2-fluoranyl-4-iodanyl-phenyl)amino]phenyl]methanone	Human	3302	0.42
MAP2K1	STE7	STE	7m0u	B		5-[(4-bromo-2-fluorophenyl)amino]-4-fluoro-n-(2-hydroxyethoxy)-1-methyl-1h-benzimidazole-6-carboxamide	Human	13517	0.45
MAP2K1	STE7	STE	6q0j	D	B	5-[(2-fluoro-4-iodophenyl)amino]-n-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide	Human	11718	0.49
MAP2K1	STE7	STE	3v04	A		4-[(2-fluoro-4-iodophenyl)amino]-n-(2-hydroxyethoxy)-1h-indazole-5-carboxamide	Human	3325	0.52
MAP2K1	STE7	STE	6q0j	D	A	5-[(2-fluoro-4-iodophenyl)amino]-n-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide	Human	11714	0.49