Searching for structures with analogs of Avutometinib.
Search results (6 entries covering 4 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MAP2K1 | STE7 | STE | 7mfd | B | n-(3-fluoro-4-{[4-methyl-2-oxo-7-(pyrimidin-2-yloxy)-2h-chromen-3-yl]methyl}pyridin-2-yl)-n'-methylsulfuric diamide | Human | 14076 | 1.00 | |||
| MAP2K1 | STE7 | STE | 9o0u | B | A | n-(3-fluoro-4-{[4-methyl-2-oxo-7-(pyrimidin-2-yloxy)-2h-chromen-3-yl]methyl}pyridin-2-yl)-n'-methylsulfuric diamide | Human | 16196 | 1.00 | ||
| MAP2K1 | STE7 | STE | 9o0v | B | B | n-(3-fluoro-4-{[4-methyl-2-oxo-7-(pyrimidin-2-yloxy)-2h-chromen-3-yl]methyl}pyridin-2-yl)-n'-methylsulfuric diamide | Human | 16185 | 1.00 | ||
| MAP2K1 | STE7 | STE | 9o2z | B | n-(3-fluoro-4-{[4-methyl-2-oxo-7-(pyrimidin-2-yloxy)-2h-chromen-3-yl]methyl}pyridin-2-yl)-n'-methylsulfuric diamide | Human | 16192 | 1.00 | |||
| MAP2K1 | STE7 | STE | 9o0u | B | B | n-(3-fluoro-4-{[4-methyl-2-oxo-7-(pyrimidin-2-yloxy)-2h-chromen-3-yl]methyl}pyridin-2-yl)-n'-methylsulfuric diamide | Human | 16188 | 1.00 | ||
| MAP2K1 | STE7 | STE | 9o0v | B | A | n-(3-fluoro-4-{[4-methyl-2-oxo-7-(pyrimidin-2-yloxy)-2h-chromen-3-yl]methyl}pyridin-2-yl)-n'-methylsulfuric diamide | Human | 16175 | 1.00 |
Avutometinib
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