KLIFS - the structural kinase database

Searching for structures with analogs of Zipalertinib.

Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details	Similarity (MFP)
FGFR2	FGFR	TK	8swe	A	A	n-{4-[4-amino-5-(4-methoxyphenyl)-7-methyl-7h-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl}prop-2-enamide	Human	15200	0.44
EGFR	EGFR	TK	8f1h	A		n-[(5p,8s,10r)-4-amino-6-methyl-5-(quinolin-3-yl)-8,9-dihydropyrimido[5,4-b]indolizin-8-yl]prop-2-enamide	Human	14947	1.00
EGFR	EGFR	TK	9kl4	A		n-[4-[4-amino-6-ethynyl-5-(3-quinolyl)pyrrolo[2,3-d]pyrimidin-7-yl]norbornan-1-yl]pyrimidine-5-carboxamide	Human	15864	0.43
EGFR	EGFR	TK	9vox	A		tas-2913	Human	15865	0.52
FGFR2	FGFR	TK	8swe	A	B	n-{4-[4-amino-5-(4-methoxyphenyl)-7-methyl-7h-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl}prop-2-enamide	Human	15201	0.44
EGFR	EGFR	TK	9klw	A		n-[4-[4-amino-6-ethynyl-5-(3-quinolyl)pyrrolo[2,3-d]pyrimidin-7-yl]norbornan-1-yl]pyrimidine-5-carboxamide	Human	15870	0.43
EGFR	EGFR	TK	9voy	A		n-[(5p,8s,10r)-4-amino-6-methyl-5-(quinolin-3-yl)-8,9-dihydropyrimido[5,4-b]indolizin-8-yl]prop-2-enamide	Human	15894	1.00