Searching for structures with analogs of Fidrisertib.
Search results (4 entries covering 1 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| ACVR1 (ALK2) | STKR | TKL | 6t8n | A | B | cyclopropyl-[4-[6-[5-(4-ethoxy-1-propan-2-yl-piperidin-4-yl)pyridin-2-yl]pyrrolo[1,2-b]pyridazin-4-yl]piperazin-1-yl]methanone | Human | 11830 | 0.77 | ||
| ACVR1 (ALK2) | STKR | TKL | 6t8n | B | A | cyclopropyl-[4-[6-[5-(4-ethoxy-1-propan-2-yl-piperidin-4-yl)pyridin-2-yl]pyrrolo[1,2-b]pyridazin-4-yl]piperazin-1-yl]methanone | Human | 11828 | 0.77 | ||
| ACVR1 (ALK2) | STKR | TKL | 6t8n | A | A | cyclopropyl-[4-[6-[5-(4-ethoxy-1-propan-2-yl-piperidin-4-yl)pyridin-2-yl]pyrrolo[1,2-b]pyridazin-4-yl]piperazin-1-yl]methanone | Human | 11831 | 0.77 | ||
| ACVR1 (ALK2) | STKR | TKL | 6t8n | B | B | cyclopropyl-[4-[6-[5-(4-ethoxy-1-propan-2-yl-piperidin-4-yl)pyridin-2-yl]pyrrolo[1,2-b]pyridazin-4-yl]piperazin-1-yl]methanone | Human | 11829 | 0.77 |
Fidrisertib
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