Searching for structures with analogs of Linperlisib.
Search results (4 entries covering 3 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Pik3cd (p110d) | PIK | Atypical | 6tnr | A | A | ~{n}-[2-methoxy-5-[7-[2-[4-(2-oxidanylpropan-2-yl)piperidin-1-yl]ethoxy]-1,3-dihydro-2-benzofuran-5-yl]pyridin-3-yl]methanesulfonamide | Mouse | 11911 | 0.53 | ||
| Pik3cd (p110d) | PIK | Atypical | 6tnr | A | B | ~{n}-[2-methoxy-5-[7-[2-[4-(2-oxidanylpropan-2-yl)piperidin-1-yl]ethoxy]-1,3-dihydro-2-benzofuran-5-yl]pyridin-3-yl]methanesulfonamide | Mouse | 11910 | 0.53 | ||
| PIK3CG (p110g) | PIK | Atypical | 4ezl | A | 2-(1-{[2-(2-aminopyrimidin-5-yl)-4-(morpholin-4-yl)pyrido[3,2-d]pyrimidin-6-yl]methyl}piperidin-4-yl)propan-2-ol | Human | 9235 | 0.41 | |||
| Pik3cd (p110d) | PIK | Atypical | 5l72 | A | n-[6-(5-methanesulfonamido-6-methoxypyridin-3-yl)-1,3-dihydro-2-benzofuran-4-yl]-2-(morpholin-4-yl)acetamide | Mouse | 9386 | 0.45 |
Linperlisib
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