Searching for structures with analogs of Voxtalisib.
Search results (4 entries covering 4 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| PIK3CG (p110g) | PIK | Atypical | 3pre | A | 2-amino-8-(trans-4-methoxycyclohexyl)-4-methyl-6-(1h-pyrazol-3-yl)pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 9198 | 0.63 | |||
| PIK3CG (p110g) | PIK | Atypical | 3ml9 | A | 2-amino-8-[trans-4-(2-hydroxyethoxy)cyclohexyl]-6-(6-methoxypyridin-3-yl)-4-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 9187 | 0.40 | |||
| PIK3CG (p110g) | PIK | Atypical | 4fa6 | A | 2-amino-8-cyclopentyl-4-methyl-6-(1h-pyrazol-4-yl)pyrido[2,3-d]pyrimidin-7(8h)-one | Human | 9191 | 0.41 | |||
| PIK3CA (p110a) | PIK | Atypical | 4tv3 | A | 2-amino-8-[trans-4-(2-hydroxyethoxy)cyclohexyl]-6-(6-methoxypyridin-3-yl)-4-methylpyrido[2,3-d]pyrimidin-7(8h)-one | Human | 9278 | 0.40 |
Voxtalisib
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