Searching for structures with analogs of Apitolisib.
Search results (4 entries covering 4 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| PIK3CG (p110g) | PIK | Atypical | 3tl5 | A | (2s)-1-(4-{[2-(2-aminopyrimidin-5-yl)-7-methyl-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl}piperazin-1-yl)-2-hydroxypropan-1-one | Human | 9160 | 1.00 | |||
| PIK3CG (p110g) | PIK | Atypical | 3l16 | A | 5-(6-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)pyridin-2-amine | Human | 9233 | 0.45 | |||
| PIK3CG (p110g) | PIK | Atypical | 4ezl | A | 2-(1-{[2-(2-aminopyrimidin-5-yl)-4-(morpholin-4-yl)pyrido[3,2-d]pyrimidin-6-yl]methyl}piperidin-4-yl)propan-2-ol | Human | 9235 | 0.46 | |||
| PIK3CG (p110g) | PIK | Atypical | 3l17 | A | 4-methyl-5-(6-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine | Human | 9185 | 0.49 |
Apitolisib
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