Searching for structures with analogs of Surufatinib.
Search results (7 entries covering 5 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MET | Met | TK | 4mxc | A | B | n-(3-fluoro-4-{[2-({3-[(methylsulfonyl)methyl]phenyl}amino)pyrimidin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | 3025 | 0.40 | ||
| FGFR1 | FGFR | TK | 8jmz | A | A | n-(2-(dimethylamino)ethyl)-1-(3-((4-((2-methyl-1h-indol-5-yl)oxy)pyrimidin-2-yl)amino)phenyl)methanesulfonamide | Human | 15228 | 1.00 | ||
| FGFR1 | FGFR | TK | 8jmz | A | B | n-(2-(dimethylamino)ethyl)-1-(3-((4-((2-methyl-1h-indol-5-yl)oxy)pyrimidin-2-yl)amino)phenyl)methanesulfonamide | Human | 15227 | 1.00 | ||
| CSF1R (FMS) | PDGFR | TK | 8jot | A | n-(2-(dimethylamino)ethyl)-1-(3-((4-((2-methyl-1h-indol-5-yl)oxy)pyrimidin-2-yl)amino)phenyl)methanesulfonamide | Human | 15255 | 1.00 | |||
| FGFR2 | FGFR | TK | 9vlm | A | ~{n}-[3-[2-[[3-[2-(dimethylamino)ethylsulfamoylmethyl]phenyl]amino]pyrimidin-4-yl]-1-methyl-indol-6-yl]propanamide | Human | 15413 | 0.48 | |||
| FGFR1 | FGFR | TK | 9vlj | A | ~{n}-[3-[2-[[3-[2-(dimethylamino)ethylsulfamoylmethyl]phenyl]amino]pyrimidin-4-yl]-1-methyl-indol-6-yl]propanamide | Human | 15673 | 0.48 | |||
| MET | Met | TK | 4mxc | A | A | n-(3-fluoro-4-{[2-({3-[(methylsulfonyl)methyl]phenyl}amino)pyrimidin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | Human | 3033 | 0.40 |
Surufatinib
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