Searching for structures with analogs of Silmitasertib.
Search results (53 entries covering 31 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| CLK2 | CLK | CMGC | 6fyl | A | A | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 10403 | 1.00 | ||
| CLK2 | CLK | CMGC | 6khe | A | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 11651 | 1.00 | |||
| CSNK2A1 (CK2a1) | CK2 | CMGC | 3pe1 | A | A | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 5487 | 1.00 | ||
| CSNK2A1 (CK2a1) | CK2 | CMGC | 3nga | B | A | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 5441 | 1.00 | ||
| CLK1 | CLK | CMGC | 6khd | A | B | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 11645 | 1.00 | ||
| CLK1 | CLK | CMGC | 6khd | C | A | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 11648 | 1.00 | ||
| EGFR | EGFR | TK | 8kfq | A | ~{n}-[3-[[6-chloranyl-2-[(1-ethylpyrazol-4-yl)amino]quinazolin-4-yl]amino]phenyl]prop-2-enamide | Human | 15367 | 0.44 | |||
| CSNK2A2 (CK2a2) | CK2 | CMGC | 9hk5 | A | A | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 15559 | 1.00 | ||
| CSNK2A2 (CK2a2) | CK2 | CMGC | 9ihi | A | B | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 15555 | 1.00 | ||
| CSNK2A2 (CK2a2) | CK2 | CMGC | 9hk5 | A | B | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 15560 | 1.00 | ||
| CSNK2A1 (CK2a1) | CK2 | CMGC | 9qrh | A | 5-[[(3~{e})-3-[4-[2-(3,4-dichlorophenyl)ethylamino]-4-oxidanylidene-butanoyl]iminopropyl]amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 16061 | 0.49 | |||
| CSNK2A1 (CK2a1) | CK2 | CMGC | 7i85 | A | A | 5-(ethylamino)benzo[c][2,6]naphthyridine-8-carboxamide | Human | 16062 | 0.57 | ||
| CSNK2A1 (CK2a1) | CK2 | CMGC | 9qsr | A | 5-[7-[(3-chloranyl-4-phenyl-phenyl)methylamino]heptylamino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 16063 | 0.52 | |||
| CSNK2A1 (CK2a1) | CK2 | CMGC | 9qss | A | 5-[8-[(3-chloranyl-4-phenyl-phenyl)methylamino]octylamino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 16065 | 0.52 | |||
| CSNK2A1 (CK2a1) | CK2 | CMGC | 3nga | A | B | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 5515 | 1.00 | ||
| PIM1 | PIM | CAMK | 5o11 | A | B | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 8657 | 1.00 | ||
| CLK1 | CLK | CMGC | 6khd | B | A | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 11644 | 1.00 | ||
| CLK1 | CLK | CMGC | 6khd | A | A | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 11646 | 1.00 | ||
| CLK3 | CLK | CMGC | 6khf | A | B | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 11649 | 1.00 | ||
| CSNK2A2 (CK2a2) | CK2 | CMGC | 6hmb | A | A | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 10994 | 1.00 | ||
| CLK1 | CLK | CMGC | 6khd | B | B | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 11647 | 1.00 | ||
| CSNK2A2 (CK2a2) | CK2 | CMGC | 6hmb | A | B | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 10995 | 1.00 | ||
| CSNK2A2 (CK2a2) | CK2 | CMGC | 8qbu | A | A | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 15029 | 1.00 | ||
| CLK4 | CLK | CMGC | 6fyv | A | A | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 10511 | 1.00 | ||
| PIM1 | PIM | CAMK | 5o11 | A | A | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 8656 | 1.00 | ||
| CLK3 | CLK | CMGC | 6khf | A | A | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 11650 | 1.00 | ||
| CLK1 | CLK | CMGC | 6khd | C | B | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 11643 | 1.00 | ||
| CSNK2A1 (CK2a1) | CK2 | CMGC | 3pe2 | A | B | 5-[(3-ethynylphenyl)amino]pyrimido[4,5-c]quinoline-8-carboxylic acid | Human | 5519 | 0.52 | ||
| CSNK2A1 (CK2a1) | CK2 | CMGC | 3pe2 | A | A | 5-[(3-ethynylphenyl)amino]pyrimido[4,5-c]quinoline-8-carboxylic acid | Human | 5508 | 0.52 | ||
| CSNK2A1 (CK2a1) | CK2 | CMGC | 9qst | A | 5-[4-[3-[(3-chloranyl-4-phenyl-phenyl)methylamino]propanoylamino]butylamino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 16101 | 0.49 | |||
| CLK3 | CLK | CMGC | 6fyp | A | A | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 10400 | 1.00 | ||
| CLK4 | CLK | CMGC | 6fyv | A | B | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 10510 | 1.00 | ||
| CSNK2A1 (CK2a1) | CK2 | CMGC | 9qrj | A | 5-[6-[(3-chloranyl-4-phenyl-phenyl)methylamino]hexylamino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 16075 | 0.52 | |||
| EPHA2 (EphA2) | Eph | TK | 6het | A | A | ~{n}-(3-chlorophenyl)-4-methyl-3-[(1-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide | Human | 11564 | 0.40 | ||
| EPHA2 (EphA2) | Eph | TK | 6het | A | B | ~{n}-(3-chlorophenyl)-4-methyl-3-[(1-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide | Human | 11560 | 0.40 | ||
| CLK3 | CLK | CMGC | 6fyp | A | B | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 10397 | 1.00 | ||
| CSNK2A2 (CK2a2) | CK2 | CMGC | 8qbu | A | B | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 15025 | 1.00 | ||
| DYRK1A | DYRK | CMGC | 7z5n | A | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 14667 | 1.00 | |||
| GSK3B | GSK | CMGC | 7z1g | A | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 14662 | 1.00 | |||
| GSK3B | GSK | CMGC | 7z1f | A | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 14663 | 1.00 | |||
| HIPK2 | DYRK | CMGC | 6p5s | A | A | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 11512 | 1.00 | ||
| HIPK2 | DYRK | CMGC | 6p5s | A | B | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 11513 | 1.00 | ||
| CSNK2A1 (CK2a1) | CK2 | CMGC | 8bgc | A | 5-[(phenylmethyl)amino]pyrimido[4,5-c]quinoline-8-carboxylic acid | Human | 14545 | 0.46 | |||
| CSNK2A1 (CK2a1) | CK2 | CMGC | 3nga | B | B | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 5511 | 1.00 | ||
| CSNK2A1 (CK2a1) | CK2 | CMGC | 9qsv | A | 5-(methylamino)benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 16074 | 0.65 | |||
| CSNK2A1 (CK2a1) | CK2 | CMGC | 9hyh | A | A | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 16077 | 1.00 | ||
| CSNK2A1 (CK2a1) | CK2 | CMGC | 3pe1 | A | B | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 5500 | 1.00 | ||
| CSNK2A1 (CK2a1) | CK2 | CMGC | 9qri | A | 5-[4-[[4-[2-(3,4-dichlorophenyl)ethylamino]-4-oxidanylidene-butanoyl]amino]butylamino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 16079 | 0.55 | |||
| CSNK2A1 (CK2a1) | CK2 | CMGC | 7i85 | A | B | 5-(ethylamino)benzo[c][2,6]naphthyridine-8-carboxamide | Human | 16080 | 0.57 | ||
| CSNK2A1 (CK2a1) | CK2 | CMGC | 3r0t | A | B | 3-(cyclopropylamino)-5-{[3-(trifluoromethyl)phenyl]amino}pyrimido[4,5-c]quinoline-8-carboxylic acid | Human | 5517 | 0.44 | ||
| CSNK2A1 (CK2a1) | CK2 | CMGC | 3nga | A | A | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 5422 | 1.00 | ||
| CSNK2A1 (CK2a1) | CK2 | CMGC | 3r0t | A | A | 3-(cyclopropylamino)-5-{[3-(trifluoromethyl)phenyl]amino}pyrimido[4,5-c]quinoline-8-carboxylic acid | Human | 5497 | 0.44 | ||
| CLK2 | CLK | CMGC | 6fyl | A | B | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | Human | 10404 | 1.00 |
Silmitasertib
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