Searching for structures with analogs of Selumetinib.
Search results (7 entries covering 6 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MAP2K1 | STE7 | STE | 2p55 | A | 2-[(4-ethynyl-2-fluorophenyl)amino]-3,4-difluoro-n-(2-hydroxyethoxy)benzamide | Human | 3327 | 0.42 | |||
| MAP2K1 | STE7 | STE | 7m0t | B | 5-[(4-bromo-2-chlorophenyl)amino]-4-fluoro-n-(2-hydroxyethoxy)-1-methyl-1h-benzimidazole-6-carboxamide | Human | 13512 | 1.00 | |||
| MAP2K1 | STE7 | STE | 3eqc | A | A | 2-[(2-chloro-4-iodophenyl)amino]-n-{[(2r)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamide | Human | 3280 | 0.41 | ||
| MAP2K1 | STE7 | STE | 4u81 | A | 8-[(4-cyclopropyl-2-fluorophenyl)amino]-n-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-7-carboxamide | Human | 3301 | 0.41 | |||
| MAP2K1 | STE7 | STE | 7m0u | B | 5-[(4-bromo-2-fluorophenyl)amino]-4-fluoro-n-(2-hydroxyethoxy)-1-methyl-1h-benzimidazole-6-carboxamide | Human | 13517 | 0.85 | |||
| MAP2K1 | STE7 | STE | 3eqc | A | B | 2-[(2-chloro-4-iodophenyl)amino]-n-{[(2r)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamide | Human | 3300 | 0.41 | ||
| MAP2K1 | STE7 | STE | 4u7z | A | 5-[(4-bromo-2-chlorophenyl)amino]-4-fluoro-n-(2-hydroxyethoxy)-1-methyl-1h-benzimidazole-6-carboxamide | Human | 3297 | 1.00 |
Selumetinib
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