Searching for structures with analogs of Ripasudil.
Search results (8 entries covering 4 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| ROCK1 | DMPK | AGC | 3d9v | A | (s)-2-methyl-1-[(4-methyl-5-isoquinoline)sulfonyl]-homopiperazine | Human | 2696 | 0.84 | |||
| CDC42BPB (MRCKb) | DMPK | AGC | 3tku | B | 5-(1,4-diazepan-1-sulfonyl)isoquinoline | Human | 4859 | 0.43 | |||
| ROCK1 | DMPK | AGC | 2esm | A | 5-(1,4-diazepan-1-sulfonyl)isoquinoline | Human | 2726 | 0.43 | |||
| CDC42BPB (MRCKb) | DMPK | AGC | 3tku | A | 5-(1,4-diazepan-1-sulfonyl)isoquinoline | Human | 4862 | 0.43 | |||
| PAK4 | STE20 | STE | 5vef | A | B | 5-(1,4-diazepan-1-sulfonyl)isoquinoline | Human | 8571 | 0.43 | ||
| PAK4 | STE20 | STE | 5vef | A | A | 5-(1,4-diazepan-1-sulfonyl)isoquinoline | Human | 8569 | 0.43 | ||
| ROCK1 | DMPK | AGC | 3d9v | B | (s)-2-methyl-1-[(4-methyl-5-isoquinoline)sulfonyl]-homopiperazine | Human | 2701 | 0.84 | |||
| ROCK1 | DMPK | AGC | 2esm | B | 5-(1,4-diazepan-1-sulfonyl)isoquinoline | Human | 2714 | 0.43 |
Ripasudil
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