Searching for structures with analogs of Pictilisib.
Search results (7 entries covering 7 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| PIK3CG (p110g) | PIK | Atypical | 3l16 | A | 5-(6-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)pyridin-2-amine | Human | 9233 | 0.62 | |||
| Pik3cb (p110b) | PIK | Atypical | 2y3a | A | 2-(1h-indazol-4-yl)-6-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4-morpholin-4-yl-thieno[3,2-d]pyrimidine | Mouse | 9402 | 1.00 | |||
| PIK3CG (p110g) | PIK | Atypical | 3l13 | A | [3-(6-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenyl]methanol | Human | 9167 | 0.64 | |||
| PIK3CG (p110g) | PIK | Atypical | 3l17 | A | 4-methyl-5-(6-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine | Human | 9185 | 0.65 | |||
| PIK3CG (p110g) | PIK | Atypical | 3dbs | A | 2-(1h-indazol-4-yl)-6-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4-morpholin-4-yl-thieno[3,2-d]pyrimidine | Human | 9230 | 1.00 | |||
| PIK3CA (p110a) | PIK | Atypical | 3zim | A | 1-[4-[[2-(1h-indazol-4-yl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-yl]methyl]piperazin-1-yl]-6-methyl-hept-5-ene-1,4-dione | Human | 9294 | 0.73 | |||
| Pik3cd (p110d) | PIK | Atypical | 2wxp | A | 2-(1h-indazol-4-yl)-6-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4-morpholin-4-yl-thieno[3,2-d]pyrimidine | Mouse | 9366 | 1.00 |
Pictilisib
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