Searching for structures with analogs of Pexidartinib.
Search results (5 entries covering 4 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| KIT | PDGFR | TK | 7khg | A | B | 5-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)methyl]-n-{[6-(trifluoromethyl)pyridin-3-yl]methyl}pyridin-2-amine | Human | 13788 | 1.00 | ||
| CSF1R (FMS) | PDGFR | TK | 4r7h | A | 5-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)methyl]-n-{[6-(trifluoromethyl)pyridin-3-yl]methyl}pyridin-2-amine | Human | 2308 | 1.00 | |||
| KIT | PDGFR | TK | 7khg | A | A | 5-[(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)methyl]-n-{[6-(trifluoromethyl)pyridin-3-yl]methyl}pyridin-2-amine | Human | 13786 | 1.00 | ||
| KIT | PDGFR | TK | 4hvs | A | 5-(1h-pyrrolo[2,3-b]pyridin-3-ylmethyl)-n-[4-(trifluoromethyl)benzyl]pyridin-2-amine | Human | 403 | 0.60 | |||
| CSF1R (FMS) | PDGFR | TK | 4hw7 | A | 5-[(5-methoxy-1h-pyrrolo[2,3-b]pyridin-3-yl)methyl]-n-[4-(trifluoromethyl)benzyl]pyridin-2-amine | Human | 2304 | 0.62 |
Pexidartinib
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