KLIFS - the structural kinase database

Searching for structures with analogs of Pamapimod.

Kinase	Family	Group	PDB	Chain	Orthosteric ligand	Organism	Details	Similarity (MFP)
BTK	Tec	TK	3pj2	A	2-({4-[2-(diethylamino)ethoxy]phenyl}amino)-6-(4-fluorophenoxy)-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one	Human	2911	0.45
MAPK14 (p38a)	MAPK	CMGC	3fly	A	6-(2,4-difluorophenoxy)-8-methyl-2-[(1-methylethyl)amino]pyrido[2,3-d]pyrimidin-7(8h)-one	Human	5113	0.76
MAPK14 (p38a)	MAPK	CMGC	3fln	C	6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2h-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8h)-one	Human	5090	0.62
MAPK14 (p38a)	MAPK	CMGC	3fmh	A	6-(2,4-difluorophenoxy)-8-methyl-2-{[(1r)-1-methyl-2-(2h-tetrazol-2-yl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-one	Human	5024	0.66
MAPK14 (p38a)	MAPK	CMGC	3flw	A	6-(2,4-difluorophenoxy)-2-{[3-hydroxy-1-(2-hydroxyethyl)propyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8h)-one	Human	5153	1.00
MAPK14 (p38a)	MAPK	CMGC	3flz	A	8-methyl-6-phenoxy-2-(tetrahydro-2h-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8h)-one	Human	5204	0.44
MAPK14 (p38a)	MAPK	CMGC	3fmk	A	6-(2,4-difluorophenoxy)-8-methyl-2-{[(1s)-1-methyl-2-(2h-tetrazol-2-yl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-one	Human	5209	0.66
MAPK14 (p38a)	MAPK	CMGC	3fls	A	6-(2,4-difluorophenoxy)-8-methyl-2-{[(1r)-1-methyl-2-(methylsulfonyl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-one	Human	5119	0.69
MAPK14 (p38a)	MAPK	CMGC	3flq	A	6-(2,4-difluorophenoxy)-8-methyl-2-{[(1s)-1-methyl-2-(methylsulfonyl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-one	Human	5168	0.69