Searching for structures with analogs of Linsitinib.
Search results (4 entries covering 3 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| IGF1R | InsR | TK | 3d94 | A | B | 3-[cis-3-(4-methylpiperazin-1-yl)cyclobutyl]-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine | Human | 6760 | 0.71 | ||
| TNK2 (ACK) | Ack | TK | 4id7 | A | cis-3-[8-amino-1-(4-phenoxyphenyl)imidazo[1,5-a]pyrazin-3-yl]cyclobutanol | Human | 3401 | 0.49 | |||
| IGF1R | InsR | TK | 3d94 | A | A | 3-[cis-3-(4-methylpiperazin-1-yl)cyclobutyl]-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine | Human | 6759 | 0.71 | ||
| IGF1R | InsR | TK | 8pyi | A | 3-[8-azanyl-1-(4-ethoxy-8-fluoranyl-2-phenyl-quinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methyl-cyclobutan-1-ol | Human | 14903 | 0.58 |
Linsitinib
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