KLIFS - the structural kinase database

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Searching for structures with analogs of Lapatinib.

Search results (7 entries covering 3 PDB structures)

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#	Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Similarity (MFP)	File
	EGFR	EGFR	TK	1xkk	A		n-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine	Human	1.00
	ERBB4 (ErbB4)	EGFR	TK	3bbt	B		n-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine	Human	1.00
	ERBB4 (ErbB4)	EGFR	TK	3bbt	D		n-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine	Human	1.00
	ERBB4 (ErbB4)	EGFR	TK	2r4b	A	A	n-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-ethylthieno[3,2-d]pyrimidin-4-amine	Human	0.50
	ERBB4 (ErbB4)	EGFR	TK	2r4b	A	B	n-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-ethylthieno[3,2-d]pyrimidin-4-amine	Human	0.50
	ERBB4 (ErbB4)	EGFR	TK	2r4b	B	A	n-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-ethylthieno[3,2-d]pyrimidin-4-amine	Human	0.50
	ERBB4 (ErbB4)	EGFR	TK	2r4b	B	B	n-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-ethylthieno[3,2-d]pyrimidin-4-amine	Human	0.50

Showing 1 to 7 of 7 entries