KLIFS - the structural kinase database

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Searching for structures with analogs of Ipatasertib.

Search in this table:

Kinase	Family	Group	PDB	Chain	Orthosteric ligand	Organism	Similarity (MFP)
AKT1	Akt	AGC	4ekl	A	(2s)-2-(4-chlorophenyl)-1-{4-[(5r,7r)-7-hydroxy-5-methyl-6,7-dihydro-5h-cyclopenta[d]pyrimidin-4-yl]piperazin-1-yl}-3-(propan-2-ylamino)propan-1-one	Human	1.00
AKT1	Akt	AGC	3ocb	A	(2s)-2-(4-chlorobenzyl)-3-oxo-3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-1-yl]propan-1-amine	Human	0.40
AKT1	Akt	AGC	3ocb	B	(2s)-2-(4-chlorobenzyl)-3-oxo-3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-1-yl]propan-1-amine	Human	0.40

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