Searching for structures with analogs of Idelalisib.
Search results (10 entries covering 7 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | Similarity (MFP) | File |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MAPK1 (Erk2) | MAPK | CMGC | 4qp1 | B | n-benzyl-9h-purin-6-amine | Human | 6080 | 0.41 | |||
| Pik3cd (p110d) | PIK | Atypical | 2wxf | A | A | 2-((9h-purin-6-ylthio)methyl)-5-chloro-3-(2-methoxyphenyl)quinazolin-4(3h)-one | Mouse | 9355 | 0.43 | ||
| PIK3CG (p110g) | PIK | Atypical | 2chw | A | 2-((9h-purin-6-ylthio)methyl)-5-chloro-3-(2-methoxyphenyl)quinazolin-4(3h)-one | Human | 9182 | 0.43 | |||
| MAPK1 (Erk2) | MAPK | CMGC | 4qp3 | A | (2s)-3-phenyl-2-(9h-purin-6-ylamino)propan-1-ol | Human | 6084 | 0.43 | |||
| PIK3CG (p110g) | PIK | Atypical | 4wwn | A | n-{(1s)-1-[7-fluoro-2-(pyridin-2-yl)quinolin-3-yl]ethyl}-9h-purin-6-amine | Human | 9226 | 0.40 | |||
| MAPK1 (Erk2) | MAPK | CMGC | 4qp3 | B | (2s)-3-phenyl-2-(9h-purin-6-ylamino)propan-1-ol | Human | 6079 | 0.43 | |||
| MAPK1 (Erk2) | MAPK | CMGC | 4qp1 | A | n-benzyl-9h-purin-6-amine | Human | 6092 | 0.41 | |||
| Pik3cd (p110d) | PIK | Atypical | 5i6u | A | 2-[(1s)-1-({6-amino-5-[(1h-pyrazol-4-yl)ethynyl]pyrimidin-4-yl}amino)ethyl]-5-chloro-3-phenylquinazolin-4(3h)-one | Mouse | 9370 | 0.42 | |||
| Pik3cd (p110d) | PIK | Atypical | 2wxf | A | B | 2-((9h-purin-6-ylthio)methyl)-5-chloro-3-(2-methoxyphenyl)quinazolin-4(3h)-one | Mouse | 9352 | 0.43 | ||
| Pik3cd (p110d) | PIK | Atypical | 4xe0 | A | 5-fluoro-3-phenyl-2-[(1s)-1-(7h-purin-6-ylamino)propyl]quinazolin-4(3h)-one | Mouse | 9368 | 0.76 |
Idelalisib
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